| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | Flt3 Ligand Human, His |
|---|---|
| Description | |
| Flt3 Ligand Human Recombinant, His Tag | |
| Accession (Primary) | P49771 |
| Synonyms | |
| Protein fosB, G0/G1 switch regulatory protein 3, FOSB, G0S3, AP-1, GOS3, GOSB, MGC42291, DKFZp686C0818, FOS-B. | |
| Introduction | |
| Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos- B include Fra-1 and Fra-2 genes. The 4 members of Fos gene family are: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins which can dimerize with proteins of the JUN family, thus forming the transcription factor complex AP-1. The FOS proteins act as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms exist for Fos B. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| FOS-B in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. | |
| Stability | |
| Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles. | |
| Applications | |
| • ELISA • Inhibition Assays • Western Blotting. | |
| Precautions | |
| Flt3 Ligand Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P49771 ) | |
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