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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0641-2 | 7 days | 2 µg | $100.00 |
Select product before adding to cart
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| CYK0641-10 | 7 days | 10 µg | $260.00 | |||
| CYK0641-100 | 7 days | 100 µg | $1,760.00 |
Product Overview | |
| Name | IL 10 Human, HEK |
|---|---|
| Description | |
| Interleukin-10 Human Recombinant, HEK | |
| Accession (Primary) | P22301 |
| Synonyms | |
| NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF, Edodekin-alpha, IL-12 p40, IL-12B, IL-12 subunit p40, NK cell stimulatory factor chain 2. | |
| Introduction | |
| Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation. | |
| Source | |
| Nicotiana benthamiana plant | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from 1mg/ml solution in 20 mM PBS buffer pH 7.4. | |
| Stability | |
| Lyophilized IL-12 p40 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-12 p40 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| HHHHHHIWEL KKDVYVVELD WYPDAPGEMV VLTCDTPEED GITWTLDQSS EVLGSGKTLT IQVKEFGDAG QYTCHKGGEV LSHSLLLLHK KEDGIWSTDI LKDQKEPKNK TFLRCEAKNY SGRFTCWWLT TISTDLTFSV KSSRGSSDPQ GVTCGAATLS AERVRGDNKE YEYSVECQED SACPAAEESL PIEVMVDAVH KLKYENYTSS FFIRDIIKPD PPKNLQLKPL KNSRQVEVSW EYPDTWSTPH SYFSLTFCVQ VQGKSKREKK DRVFTDKTSA TVICRKNASI SVRAQDRYYS SSWSEWASVP CS | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IL-12 p40 in sterile 18M?-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Serological Identification | |
| The protein was electrophoresed under reducing condition on a 15% SDS-polyacrylamide gel, transferred by electro blotting to a NC membrane and visualized by immune-detection with specific IL12 antibody. | |
| Precautions | |
| IL 10 Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P22301 ) | |
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