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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | IL 15 Mouse |
|---|---|
| Description | |
| Interleukin-15 Mouse Recombinant | |
| Accession (Primary) | P48346 |
| Synonyms | |
| CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8. | |
| Introduction | |
| IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IL17 was lyophilized from 1mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized IL-17 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL17 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent induction of IL-6 secretion from NDHF Adult fibroblasts and is typically 5-25ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IL-17 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IL 15 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P48346 ) | |
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