| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0646-2 | 7 days | 2 µg | $100.00 |
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| CYK0646-10 | 7 days | 10 µg | $260.00 | |||
| CYK0646-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | IL 17F Human, HEK |
|---|---|
| Description | |
| Interleukin-17F Human Recombinant, HEK | |
| Accession (Primary) | Q96PD4 |
| Synonyms | |
| T-cell growth factor (TCGF), Interleukin-2, Lymphokine, IL-2. | |
| Introduction | |
| IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IL2 was lyophilized from 0.2 µm filtered solution containing 1mg/ml protein in 1xPBS. | |
| Stability | |
| Lyophilized IL-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Amino acid sequence | |
| APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLE EELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line) and is typically 0.2-2ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IL-2 in sterile PBS containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| IL 17F Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96PD4 ) | |
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