Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0649-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
|
||
| CYK0649-10 | 7 days | 10 µg | $290.00 | |||
| CYK0649-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | IL 22 Mouse, PEG |
|---|---|
| Description | |
| Interleukin-22 Mouse Recombinant, Pegylated | |
| Accession (Primary) | Q9JJY9 |
| Synonyms | |
| Interleukin 23 alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturation factor 2 p40), NK cell stimulatory factor chain 2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF2, CLMF p40. | |
| Introduction | |
| IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kB pathways and stimulate the production of IFN-gamma. ). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| IL-23 if supplied as a sterile filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| IL-23 was lyophilized from a 0.1 µm filtered solution (1.05mg/ml) containing 1xPBS. | |
| Stability | |
| Lyophilized Interleukin-23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-23 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by analysis by SDS-PAGE. | |
| Biological Activity | |
| The activity, as determined by the dose dependent secretion of IL-17 in response to IL-23 using murine splenocytes, the ED 50 is 1.9ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IL23 in sterile 1xPBS containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| IL 22 Mouse, PEG is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9JJY9 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
