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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | IL 28A Human, HEK |
|---|---|
| Description | |
| Interleukin-28A Human Recombinant, HEK | |
| Accession (Primary) | Q8IZJ0 |
| Synonyms | |
| Interleukin-28B, IL-28B, Cytokine Zcyto22, Interferon lambda-3, IFN-lambda-3, Interleukin-28C, IL-28C, IL28B, IFNL3, IL28C, ZCYTO22. | |
| Introduction | |
| IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IL28B was lyophilized from 1mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL28B should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus and is typically 0.1-1ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IL-28B in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IL 28A Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8IZJ0 ) | |
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ADMEbio Team
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