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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| CYK0659-2 | 7 days | 2 µg | $120.00 |
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| CYK0659-10 | 7 days | 10 µg | $290.00 | |||
| CYK0659-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | IL-22 Antagonist Mouse |
|---|---|
| Description | |
| Interleukin-22 Antagonist (E117A) Mouse Recombinant | |
| Accession (Primary) | Q9JJY9 |
| Synonyms | |
| Interleukin 34, C16orf77, MGC34647, IL34. | |
| Introduction | |
| Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response and bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity and in inflammatory processes. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The IL34 was lyophilized from a solution containing 20mM Sodium Citrate, pH 3.0 and 75mM NaCl. | |
| Stability | |
| Lyophilized IL34 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Interleukin 34 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP QGLTDVEVSP APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH. | |
| Biological Activity | |
| The specific activity was measured by its ability to induce secretion of MCP-1 from PBMCs. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Interleukin-34 in sterile 18M-cm H 2 O containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| IL-22 Antagonist Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9JJY9 ) | |
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