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>   Home   >   Products   >   Primary Antibodies   >   FADD Rabbit mAb   

FADD Rabbit mAb

 
Catalog #
ABZ2031
Application
WB, IF, FC, IP, ICC, IHC-P
Uniprot Id
Q61160
Reactivity
Mouse
Isotype
IgG
 
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  • Immunohistochemistry analysis of paraffin-embedded mouse liver using FADD antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.
  • Western blot analysis of FADD in SH-SY5Y lysates using FADD antibody
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2031-100 2 weeks 100 µL $499.00
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ABZ2031-20 2 weeks 20 µL $149.00
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Product Overview

NameFADD Rabbit mAb
Accession (Primary)Q61160
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithMouse
Calculated MW
Calculated MW: 23 kDa; Observed MW: 28 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100; IF-1:50-1:200
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .

Target Information: ( Q61160 )

NameFadd
Gene ID14082
Other Names
FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
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