| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4166-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4166-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | FYB (2H9) Mouse mAb |
|---|---|
| Accession (Primary) | O15117 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 85 kDa; Observed MW: 120 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (PubMed:10747096, PubMed:16980616). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 (PubMed:15849195). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity). | |
Target Information: ( O15117 ) | |
| Name | FYB1 |
| Gene ID | 2533 |
| Other Names | |
| ADAP; Fyb; FYN binding protein; p120/p130; SLAP130; FYB 120/130; | |
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ADMEbio Team
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ADMEbio Team