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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2954-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2954-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Fibrillarin Rabbit mAb |
|---|---|
| Accession (Primary) | P22087 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 34 kDa; Observed MW: 34 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; ICC/IF-1:500-1:5000; FC-1:10-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development. | |
Target Information: ( P22087 ) | |
| Name | FBL |
| Gene ID | 2091 |
| Other Names | |
| FIB; FLRN; Nop1; RNU3IP1; Fibrillarin/U3 RNP; 34 kD nucleolar scleroderma antigen; 34 kDa nucleolar scleroderma antigen; Fbl; | |
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ADMEbio Team
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ADMEbio Team
