| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4194-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4194-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | GADD45A (6C3) Mouse mAb |
|---|---|
| Accession (Primary) | P24522 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 18 kDa; Observed MW: 22 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. | |
Target Information: ( P24522 ) | |
| Name | GADD45A |
| Gene ID | 1647 |
| Other Names | |
| DDIT1; GADD45 | |
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