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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0045-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| GRF0045-50 | 7 days | 50 µg | $290.00 | |||
| GRF0045-1 | 7 days | 1 mg | $2,160.00 |
Product Overview | |
| Name | EPO a Human |
|---|---|
| Description | |
| Erythropoietin-Alpha Human Recombinant | |
| Accession (Primary) | P01588 |
| Synonyms | |
| Erythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, MGC138142. | |
| Introduction | |
| This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The EPO-alpha was lyophilized from 1mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized EPO-alpha although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EPO-alpha should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line) and is typically 0.5-2.5ng/ml, corresponding to a specific activity of 400,000-2,000,000 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized EPO-alpha in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| EPO a Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01588 ) | |
References |
1. Title :Zinc Transporters ZnT1 (Slc30a1), Zip8 (Slc39a8), and Zip10 (Slc39a10) in Mouse Red Blood Cells Are Differentially Regulated during Erythroid Development and by Dietary Zinc Deficiency 1–3 Publication :Journal of Nutrition, doi:10.3945/jn.108.093575 Vol. 138, No. 11, 2076-2083, November 2008 © 2008 American Society for Nutrition J. Nutr. 138:2076-2083, November 2008 Link : EPO a prospec publication 2. Title :Systemically delivered Erythropoietin transiently enhances adult hippocampal neurogenesis. Publication :Article first published online: 7 MAY 2007 DOI:10.1111/j.1471-4159.2007.04684.x Journal of Neurochemistry Volume 102, Issue 6, pages 1953–1965, September 2007. Link : EPO a Human prospec publication 3. Title :ZINC TRANSPORTER EXPRESSION IN MATURE RED BLOOD CELLS AND DIFFERENTIATING ERYTHROID PROGENITOR CELLS. Publication :UNIVERSITY OF FLORIDA © 2007 Moon-Suhn Ryu Link : EPO a Protein prospec publication 4. Title :Cell Therapy with Human Renal Cell Cultures Containing Erythropoietin-Positive Cells Improves Chronic Kidney Injury. Publication :First Published Online May 3, 2012 doi: 10.5966/sctm.2011-0048 Stem Cells Trans Med May 2012 vol. 1 no. 5 373-383 Link : Erythropoietin-Alpha prospec publication |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
