| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0046-2 | 7 days | 2 µg | $120.00 |
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| GRF0046-10 | 7 days | 10 µg | $290.00 | |||
| GRF0046-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | EPO a Human, HEK |
|---|---|
| Description | |
| Erythropoietin-alpha Human Recombinant, HEK | |
| Accession (Primary) | P01588 |
| Synonyms | |
| Erythropoietin, EP, INN=Epoetin, EPO a, Erythropoietin-alpha, EPO. | |
| Introduction | |
| EPO a is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. EPO a is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. EPO a also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| EPO a protein solution (0.5mg/ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALRAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR LEHH HHHH. | |
| Biological Activity | |
| The ED50 range is ≤0.5ng/ml and measured in a cell proliferation assay using TF-1 human erythroleukemic cells. | |
| Precautions | |
| EPO a Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01588 ) | |
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