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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0064-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| GRF0064-50 | 7 days | 50 µg | $290.00 | |||
| GRF0064-1 | 7 days | 1 mg | $1,728.00 |
Product Overview | |
| Name | FGF 2 Human (147 a.a.) |
|---|---|
| Description | |
| Fibroblast Growth Factor Basic 147 a.a. Human Recombinant | |
| Accession (Primary) | P09038 |
| Synonyms | |
| Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2. | |
| Introduction | |
| Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. | |
| Source | |
| Rice Grain (Oryza Sativa). | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| FGF-b was lyophilized from a concentrated solution without any additives. | |
| Stability | |
| Lyophilized Fibroblast Growth Factor-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-b should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Biological Activity | |
| The ED 50 , as calculated by the dose-dependent proliferation of Balb/c 3T3 cells expressing FGF receptors is < 1 ng/ml, corresponding to a specific activity of > 1 x10 6 Units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Fibroblast Growth Factor Basic in sterile 18MΩ-cm H2O at 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| FGF 2 Human (147 a.a.) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P09038 ) | |
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ADMEbio Team
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