| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0101-2 | 7 days | 2 µg | $120.00 |
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| GRF0101-10 | 7 days | 10 µg | $290.00 | |||
| GRF0101-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | FGF23 Human, Sf9 |
|---|---|
| Description | |
| Fibroblast Growth Factor-23 Human Recombinant, Sf9 | |
| Accession (Primary) | Q9GZV9 |
| Synonyms | |
| HBGF4, FGF-4, FGF4, KFGF, HSTF1. | |
| Introduction | |
| FGF4 holds s comprehensive mitogenic and cell survival activities and takes part in a range of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF4 possess oncogenic transforming activity. FGF4 and FGF3, oncogenic growth factors are localized on chromosome 11. Co-amplification of both factors was found in several kinds of human tumors. FGF4 functions in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The FGF4 protein was lyophilized with 2xPBS, pH 7.4. | |
| Stability | |
| Lyophilized FGF4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-4 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL. | |
| Biological Activity | |
| The ED 50 as determined by NR6R-3T3 Proliferation is 0.543ng/ml, corresponding to a specific activity of 1.8X10 6 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized FGF4 Human Recombinant sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| FGF23 Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9GZV9 ) | |
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