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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0104-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| GRF0104-25 | 7 days | 25 µg | $290.00 | |||
| GRF0104-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | FGF6 Human |
|---|---|
| Description | |
| Fibroblast Growth Factor-6 Human Recombinant | |
| Accession (Primary) | P10767 |
| Synonyms | |
| FGF8B, FGF-8B, FGF8-B, KAL6, HBGF-8, HBGF8, AIGF, HBGF-8, MGC149376, fibroblast growth factor 8. | |
| Introduction | |
| FGF8 is part of the fibroblast growth factor family. FGF family members have wide mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF8 supports androgen and anchorage independent growth of mammary tumor cells. FGF8 over expression increases tumor growth and angiogensis. The adult expression of FGF-8 gene is restricted to testes and ovaries. FGF8 functions as an embryonic epithelial factor. FGF8 takes part in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The FGF-8 solution (0.25mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as obsereved by SDS-PAGE. | |
| Amino acid sequence | |
| DGSHMQVTVQ SSPNFTQHVR EQSLVTDQLS RRLIRTYQLY SRTSGKHVQV LANKRINAMA EDGDPFAKLI VETDTFGSRV RVRGAETGLY ICMNKKGKLI AKSNGKGKDC VFTEIVLENN YTALQNAKYE GWYMAFTRKG RPRKGSKTRQ HQREVHFMKR LPRGHHTTEQ SLRFEFLNYP PFTRSLRGSQ RTWAPEPR HH HHHH . | |
| Biological Activity | |
| The ED50 is ≤5 µg/ml, measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells in the presence of 10ug/ml of heparin. | |
| Precautions | |
| FGF6 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P10767 ) | |
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ADMEbio Team
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