| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0112-2 | 7 days | 2 µg | $120.00 |
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| GRF0112-10 | 7 days | 10 µg | $290.00 | |||
| GRF0112-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | G CSF Human, PEG |
|---|---|
| Description | |
| Granulocyte-Colony Stimulating Factor Pegylated Human Recombinant | |
| Accession (Primary) | P09919 |
| Synonyms | |
| CSF3, MGI-1G, GM-CSF beta, Pluripoietin, G-CSF, GCSF. | |
| Introduction | |
| Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| G-CSF Lyophilized from 10mM NaCitrate, pH 4.0 and 150mM NaCl. | |
| Stability | |
| Lyophilized Granulocyte Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GCSF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| VPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA. | |
| Biological Activity | |
| The ED 50 as determined by a cell proliferation assay using murine NFS-60 cells is < 0.05 ng/ml, corresponding to a Specific Activity of 2 x 10 7 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Granulocyte Colony Stimulating Factor in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| G CSF Human, PEG is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P09919 ) | |
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