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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0122-10 | 7 days | 10 µg | $160.00 |
Select product before adding to cart
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| GRF0122-50 | 7 days | 50 µg | $360.00 | |||
| GRF0122-1 | 7 days | 1 mg | $4,080.00 |
Product Overview | |
| Name | GH Human 20kDa |
|---|---|
| Description | |
| Growth Hormone Pituitary 20kDa Human Recombinant | |
| Accession (Primary) | P01241 |
| Synonyms | |
| GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin. | |
| Introduction | |
| GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The GH was lyophilized from 1.13mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized GH although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The activity was determined by the dose dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line), the ED 50 is 0.1ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized GH in sterile 1xPBS containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| GH Human 20kDa is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01241 ) | |
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ADMEbio Team
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