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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0130-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| GRF0130-50 | 7 days | 50 µg | $290.00 | |||
| GRF0130-1 | 7 days | 1 mg | $3,680.00 |
Product Overview | |
| Name | GH Zebrafish |
|---|---|
| Description | |
| Growth Hormone Zebrafish Recombinant | |
| Immunogen | |
| GH Antibody is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant Growth hormone. | |
| Synonyms | |
| GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin. | |
| Introduction | |
| GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. | |
| Physical Appearance | |
| Sterile Filtered solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% sodium azide. | |
| Applications | |
| The GH antibody has been tested by ELISA and by Western blot analysis to assure specificity and reactivity. Since application vary, however, each investigation should titrate the reagent to obtain optimal results. Recommended dilution range for Western blot analysis: 1:500 ~ 1:1000. Recommended starting dilution: 1:500. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PG3H5AT. | |
| Ig Subclass | |
| Mouse IgG 2b heavy chain and k light chain. | |
| Purification Method | |
| GH antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4 C, for longer periods of time, store at -20 C. Prevent freeze thaw cycles. | |
| Precautions | |
| GH Zebrafish is for research use only and not for use in diagnostic or therapeutic procedures. | |
References |
Title :Growth Hormone Promotes Hair Cell Regeneration in the Zebrafish ( Danio rerio ) Inner Ear following Acoustic Trauma. Publication: Sun H, Lin C-H, Smith ME (2011) Growth Hormone Promotes Hair Cell Regeneration in the Zebrafish ( Danio rerio ) Inner Ear following Acoustic Trauma. PLoS ONE 6(11): e28372. doi:10.1371/journal.pone.0028372 Link : GH Zebrafish prospec publication |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
