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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0167-50 | 7 days | 50 µg | $900.00 |
Select product before adding to cart
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| GRF0167-100 | 7 days | 100 µg | $1,400.00 | |||
| GRF0167-1 | 7 days | 1 mg | $5,600.00 |
Product Overview | |
| Name | IGF1 Human, R36Q |
|---|---|
| Description | |
| Insulin Like Growth Factor-1, Mutant R36Q Human Recombinant | |
| Accession (Primary) | P05019 |
| Synonyms | |
| Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF. | |
| Introduction | |
| The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that takes part in mammalian growth and development. IGF1 mediates various growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). 3 main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003). | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| IGF1 V44M Lyophilized from a 0.2 µm filtered concentrated solution in PBS. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIMDECCFR SCDLRRLEMY. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IGF1 V44M in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IGF1 Human, R36Q is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05019 ) | |
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ADMEbio Team
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