| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0170-10 | 7 days | 10 µg | $160.00 |
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| GRF0170-50 | 7 days | 50 µg | $360.00 | |||
| GRF0170-1 | 7 days | 1 mg | $4,400.00 |
Product Overview | |
| Name | IGF1 N15 Human |
|---|---|
| Description | |
| Insulin Like Growth Factor-1 N15 Labeled Human Recombinant | |
| Accession (Primary) | P05019 |
| Immunogen | |
| Anti-human IGF1 mAb, clone PAT6F8AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IGF1 protein 49-118 amino acids purified from E. coli. | |
| Synonyms | |
| Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF. | |
| Introduction | |
| The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003). | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| HSPA5 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT6F8AT. | |
| Ig Subclass | |
| Mouse IgG 2b heavy chain and k light chain. | |
| Purification Method | |
| IGF1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| IGF1 N15 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05019 ) | |
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ADMEbio Team
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