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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0174-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| GRF0174-50 | 7 days | 50 µg | $290.00 | |||
| GRF0174-1 | 7 days | 1 mg | $2,016.00 |
Product Overview | |
| Name | IGF2 Mouse |
|---|---|
| Description | |
| Insulin Like Growth Factor-2 Mouse Recombinant | |
| Accession (Primary) | P09535 |
| Synonyms | |
| IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1. | |
| Introduction | |
| IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. | |
| Source | |
| Mouse myeloma cell line, NS0. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| IGFBP-1 protein was lyophilized from a 0.2 µm filtered concentrated solution in PBS. | |
| Stability | |
| Lyophilized IGFBP1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGF-BP1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| APWQCAPCSA EKLALCPPVS ASCSEVTRSA GCGCCPMCAL PLGAACGVAT ARCARGLSCR ALPGEQQPLH ALTRGQGACV QESDASAPHA AEAGSPESPE STEITEEELL DNFHLMAPSE EDHSILWDAI STYDGSKALH VTNIKKWKEP CRIELYRVVE SLAKAQETSG EEISKFYLPN CNKNGFYHSR QCETSMDGEA GLCWCVYPWN GKRIPGSPEI RGDPNCQIYF NVQN. | |
| Biological Activity | |
| The ED 50 , as determined by the inhibition of rHuIGF-I-induced proliferation of human MCF-7 cells, is less than 4 µg/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized IBP-1 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| IGF2 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P09535 ) | |
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ADMEbio Team
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