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Insulin Human

Insulin Human Recombinant

 
Catalog #
GRF0189
Uniprot Id
P01308
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
GRF0189-25 7 days 25 mg $350.00
Select product before adding to cart
GRF0189-250 7 days 250 mg $880.00
GRF0189-1 7 days 1gr $2,288.00
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Product Overview

NameInsulin Human
Description
Insulin Human Recombinant
Accession (Primary)P01308
Source
Escherichia Coli.
Physical Appearance
Filtered White lyophilized (freeze-dried) powder.
Formulation
Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT.
Stability
Store lyophilized Insulin at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.
Background
Insulin participates in the metabolism of carbohydrates, proteins and fats by regulating glucose homeostasis in the body. Insulin decreases blood glucose concentration. Insulin hormone facilitates the uptake of glucose into cells, mainly in muscle and fat tissues, and stimulates the liver to store glucose as glycogen. Insulin also inhibits the production of gluconeogenesis and promotes the synthesis of proteins and lipids. Insulin increases cell permeability to monosaccharides, fatty acids and amino acids. Insulin accelerates glycolysis, the pentose phosphate cycle and glycogen synthesis in liver.
Precautions
Insulin Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P01308 )

References

Title: PI3K integrates the effects of insulin and leptin on large-conductance Ca2+-activated K+ channels in neuropeptide Y neurons of the hypothalamic arcuate nucleus Publication: American Journal of Physiology-Endocrinology and Metabolism 298.2 (2010): E193-E201. Link: Insulin prospec publication

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