| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0260-5 | 7 days | 5 µg | $120.00 |
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| GRF0260-20 | 7 days | 20 µg | $290.00 | |||
| GRF0260-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | MIA Human, His |
|---|---|
| Description | |
| Melanoma Inhibitory Activity Protein Human Recombinant, His Tag | |
| Accession (Primary) | Q16674 |
| Synonyms | |
| MIA-2, MIA2, Melanoma Inhibitory Activity 2, FLJ22404. | |
| Introduction | |
| MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF-B & and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The MIA2 protein was lyophilized from a concentrated (1mg/ml) solution containing 20mM Phosphate buffer pH=7.4 and 150mM NaCl. | |
| Stability | |
| Lyophilized MIA2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MIA2 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized MIA2 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| MIA Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q16674 ) | |
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