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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0273-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| GRF0273-10 | 7 days | 10 µg | $290.00 | |||
| GRF0273-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | Myostatin Human, His |
|---|---|
| Description | |
| Myostatin Human Recombinant, His Tag | |
| Accession (Primary) | O14793 |
| Synonyms | |
| GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy. | |
| Introduction | |
| Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered white lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized with no additives. | |
| Stability | |
| Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRR. | |
| Biological Activity | |
| The protein has full biological activity when compared to a standard. The activity is determined by its ability to inhibit 50ng/ml of Myostatin on MPC-11 cells and is typically 0.13-0.2 µg/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Myostatin Propeptide in sterile 20mM HCl at 0.1mg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| Myostatin Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O14793 ) | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
