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Omentin 298 a.a. Human

Omentin 298 a.a. Human Recombinant

 
Catalog #
GRF0284
Uniprot Id
Q8WWA0
 
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GRF0284-5 7 days 5 µg $120.00
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GRF0284-20 7 days 20 µg $290.00
GRF0284-1 7 days 1 mg $4,320.00
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Product Overview

NameOmentin 298 a.a. Human
Description
Omentin 298 a.a. Human Recombinant
Accession (Primary)Q8WWA0
Immunogen
Anti-human Omentin mAb, clone PAT6C11AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Omentin protein 17-313 amino acids purified from E. coli.
Synonyms
Intelectin-1, HL1, LFR, HL-1, INTL, ITLN, hIntL.
Introduction
Omentin is a recently recognized gene highly localized to the mental tissue (visceral adipose tissue). Omentin is present in the stromal vascular cells in the adipose tissue rather than in the adipocytes. Omentin is predominantly expressed in the visceral adipose tissue than the subcutaneous tissue, with the omentin mRNA being 150 times higher in the visceral adipose tissue. Omentin has also been detected in human blood using western blot analysis, and seems to increase insulin-stimulated glucose uptake in 3T3-L1 adipocytes in mice. Omentin seems to increase Akt phosphorylation irrespective of insulin presence. Its role in glucose metabolism and obesity remains to be described; an insulin-sensitizing action is possible.Differences in Omentin expression has been noted in adipose tissue from normals and patients with inflammatory bowel disease although its significance is unknown
Physical Appearance
Sterile filtered colorless solution.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Applications
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:250.
Type
Mouse Anti Human Monoclonal.
Clone
PAT6C11AT.
Ig Subclass
Mouse IgG1 heavy chain and Kappa light chain.
Purification Method
Omentin antibody was purified by protein-A affinity chromatography.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Precautions
Omentin 298 a.a. Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q8WWA0 )

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