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PDGF AB Human

Platelet-Derived Growth Factor AB Human Recombinant

 
Catalog #
GRF0305
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
GRF0305-2 7 days 2 µg $120.00
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GRF0305-10 7 days 10 µg $290.00
GRF0305-1 7 days 1 mg $5,616.00
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Product Overview

NamePDGF AB Human
Description
Platelet-Derived Growth Factor AB Human Recombinant
Synonyms
Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, SIS, SSV, PDGF2, c-sis, FLJ12858, PDGF-BB, PDGF B-chain, Platelet-derived growth factor beta polypeptide, Becaplermin.
Introduction
The term ‘PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
Platelet-Derived Growth Factor-B is supplied in 25mM Na-Acetate pH 4.8, 1mM EDTA and 50% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Precautions
PDGF AB Human is for research use only and not for use in diagnostic or therapeutic procedures.
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