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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0310-2 | 7 days | 2 µg | $120.00 |
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| GRF0310-10 | 7 days | 10 µg | $290.00 | |||
| GRF0310-1 | 7 days | 1 mg | $5,616.00 |
Product Overview | |
| Name | PDGF BB Rat |
|---|---|
| Description | |
| Platelet-Derived Growth Factor BB Rat Recombinant | |
| Accession (Primary) | Q05028 |
| Synonyms | |
| Platelet Derived Growth Factor C, Spinal Cord-Derived Growth Factor, FALLOTEIN, PDGF-C, VEGF-E, SCDGF, Secretory Growth Factor-Like Protein, Platelet-Derived Growth Factor C, PDGFC. | |
| Introduction | |
| Platelet Derived Growth Factor-CC (PDGF-CC) belongs to the PGDF family of growth factors. PDGF-CC binds with high-affinity to PDGF R-a and activates PDGF R-ab heterodimers. During development, PDGF-CC is involved in ductal morphogenesis, cardiovascular smooth muscle cell proliferation; also PDGF-CC is an angiogenic factor. Furthermore, PDGF-CC is expressed in numerous tumors and tumor cell lines, and may be linked with tumorigenesis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA. | |
| Stability | |
| Lyophilized PDGF-CC although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PDGF-CC should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MHHHHHHVVD LNLLTEEVRL YSCTPRNFSV SIREELKRTD TIFWPGCLLV KRCGGNCACC LHNCNECQCV PSKVTKKYHE VLQLRPKTGV RGLHKSLTDV ALEHHEECDC VCRGSTGG. | |
| Biological Activity | |
| The ED 50 , as measured in a proliferation assay using mouse NR6R-3T3 cells, is less than 350ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized PDGF-CC in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PDGF BB Rat is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q05028 ) | |
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ADMEbio Team
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ADMEbio Team
