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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0318-5 | 7 days | 5 µg | $120.00 |
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| GRF0318-10 | 7 days | 10 µg | $290.00 | |||
| GRF0318-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | PGF1 Mouse |
|---|---|
| Description | |
| Placental Growth Factor-1 Mouse Recombinant | |
| Accession (Primary) | P49764 |
| Synonyms | |
| GHL, GHV, GH-V, hGH-V, PGH. | |
| Introduction | |
| GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| pGH 20kDa was lyophilized from a concentrated (1mg/ml) solution with0.0045mM NaHCO3 previously adjusted pH 11. | |
| Stability | |
| Lyophilized Growth Hormone 20K Placental although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution and filter sterilization GH 20K pl can be stored at 4°C for up to 4 weeks. For long term storage and more diluted solutions it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AFPTI PLSRLFDNAM LRARRLYQLA YDTYQEFNPQ TSLCFSESIP TPSNRVKTQQ KSNLELLRIS LLLIQSWLEP VQLLRSVFAN SLVYGASDSN VYRHLKDLEE GIQTLMWRLE DGSPRTGQIF NQSYSKFDTK SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Placental Growth Hormone in 0.4% NaHCO3or water adjusted to pH 11, not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PGF1 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P49764 ) | |
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