| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0336-2 | 7 days | 2 µg | $120.00 |
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| GRF0336-10 | 7 days | 10 µg | $290.00 | |||
| GRF0336-1 | 7 days | 1 mg | $4,800.00 |
Product Overview | |
| Name | PLGF2 Human |
|---|---|
| Description | |
| Placental Growth Factor-2 Human Recombinant | |
| Accession (Primary) | P49763 |
| Synonyms | |
| PIGF, PGF, PlGF-2, PLGF-2. | |
| Introduction | |
| PLGF is a growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration. It binds to receptor vegfr-1/flt1. PLGF-2 binds neuropilin-1 and 2 in a heparin-dependent manner. | |
| Source | |
| Chinese Hamster Ovary cells (CHO). | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| PLGF-2 protein was lyophilized from a 0.2 µm filtered solution in HCl. | |
| Stability | |
| Lyophilized PLGF-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PLGF2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR. | |
| Biological Activity | |
| The ED 50 , as measured in a cell proliferation assay using MDA?MB?231 cells is less than 10 µg/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized PLGF2 at 200 µg/ml in PBS, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PLGF2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P49763 ) | |
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