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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0354-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| GRF0354-50 | 7 days | 50 µg | $290.00 | |||
| GRF0354-1 | 7 days | 1 mg | $2,880.00 |
Product Overview | |
| Name | Prolactin Ovine, His |
|---|---|
| Description | |
| Ovine Prolactin Recombinant, His Tag | |
| Accession (Primary) | P01240 |
| Synonyms | |
| Mammotropin, Luteotropic hormone, Luteotropin, PRL. | |
| Introduction | |
| Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. | |
| Stability | |
| Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prl should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Ile-Cys. | |
| Biological Activity | |
| The ED50 as determined by the dose-dependant stimulation of the proliferation of rat lymphoma, Nb2-11 was found to be < 0.065ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Prolactin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Protein content | |
| Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.87 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of Prolactinl as a Reference Standard. | |
| Precautions | |
| Prolactin Ovine, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01240 ) | |
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ADMEbio Team
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ADMEbio Team
