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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0391-1 | 7 days | 1 µg | $120.00 |
Select product before adding to cart
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| GRF0391-5 | 7 days | 5 µg | $290.00 | |||
| GRF0391-100 | 7 days | 100 µg | $2,400.00 |
Product Overview | |
| Name | TGFB2 Human |
|---|---|
| Description | |
| Transforming Growth Factor Beta 2 Human Recombinant | |
| Accession (Primary) | P61812 |
| Synonyms | |
| Transforming growth factor, beta 2, cetermin, Glioblastoma-derived T-cell suppressor factor, polyergin, G-TSF, TGF-beta2, TGF-beta-2, transforming growth factor beta-2, BSC-1 cell growth inhibitor, TGFB-2. | |
| Introduction | |
| TGFB2 is a 27.08 kDa protein having two identical 118 amino acid peptide chains linked by a single disulfide bond. TGFB2 is part of a family of five related cytokines that have an extensive variation of normal and neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF-beta (TGFb1, TGFb2 and TGFb3) signal through the same receptor and stimulate similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| TGF-b 2 was lyophilized from a 0.2 µm filtered solution containing 50mM sodium acetate pH 4.5. | |
| Stability | |
| Lyophilized TGF-b 2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TGF-b 2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2), the ED 50 is 0.16ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized TGF-b 2 in sterile solution containing 20% ethanol, 50mM sodium acetate and 75mM acetic acid. | |
| Precautions | |
| TGFB2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P61812 ) | |
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ADMEbio Team
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