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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0396-1 | 7 days | 1 µg | $120.00 |
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|
Product Overview | |
| Name | TGFB3 Human, HEK |
|---|---|
| Description | |
| Transforming Growth Factor-Beta 3 Human Recombinant, HEK | |
| Accession (Primary) | P10600 |
| Synonyms | |
| Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3. | |
| Introduction | |
| Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. | |
| Source | |
| Nicotiana benthamiana. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a concentrated (1mg/ml) solution containing 50mM Tris-HCl pH-7.4. | |
| Stability | |
| Lyophilized TGFB3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TGFB3 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| HHHHHALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKG YYANFCSGPCPYLRSADTTHSTVLGLY NTLNPEASASP CCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS. | |
| Biological Activity | |
| The biological activity of TGFB3 is measured in culture by its ability to inhibit the mink lung epithelial (Mv1Lu) cells proliferation. ED50 ? 40ng/ml corresponding to a specific activity of 25,000 Units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized TGFB3 in sterile 5mM HCl & 50ug/ml BSA at a concentration of 0.05mg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| TGFB3 Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P10600 ) | |
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ADMEbio Team
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