| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0405-2 | 7 days | 2 µg | $120.00 |
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| GRF0405-10 | 7 days | 10 µg | $290.00 | |||
| GRF0405-1 | 7 days | 1 mg | $8,160.00 |
Product Overview | |
| Name | VEGF C Rat (152 a.a.) |
|---|---|
| Description | |
| Vascular Endothelial Growth Factor-C (152 a.a) Rat Recombinant | |
| Accession (Primary) | O35757 |
| Synonyms | |
| c-fos induced growth factor (vascular endothelial growth factor D), FIGF, VEGFD. | |
| Introduction | |
| VEGF-D belongs to the VEGF/PDGF family of proteins. VEGF-D promotes lymphangiogesis, endothelial cell growth, and regulates vascular permeability. In addition, VEGF-D has an important part in the creation of the venous and lymphatic vascular systems and in the growth and maintenance of differentiated lymphatic endothelium Mature VEGF-D forms a noncovalently linked homodimer, and binds to and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4). | |
| Source | |
| HEK293. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The recombinant VEGF-D was lyophilized after extensive dialysis against PBS. | |
| Stability | |
| Lyophilized VEGF-D although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution VEGF-D should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Biological Activity | |
| The ED50 of 3-4ng/ml is measured by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVECs). | |
| Solubility | |
| It is recommended to reconstitute the Vascular Endothelial Growth Factor D in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| VEGF C Rat (152 a.a.) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O35757 ) | |
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