| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0433-2 | 7 days | 2 µg | $220.00 |
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| GRF0433-5 | 7 days | 5 µg | $380.00 | |||
| GRF0433-10 | 7 days | 10 µg | $464.00 |
Product Overview | |
| Name | FGF 2 Bovine |
|---|---|
| Description | |
| Fibroblast Growth Factor Basic Bovine | |
| Accession (Primary) | P03969 |
| Synonyms | |
| Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b. | |
| Introduction | |
| Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The FGF-2 was lyophilized from 1mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized FGF-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-b should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line and is typically 0.1- 0.5ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized FGF-b in sterile PBS containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| FGF 2 Bovine is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P03969 ) | |
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