| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0457-50 | 7 days | 50 µg | $1,300.00 |
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| GRF0457-100 | 7 days | 100 µg | $1,900.00 | |||
| GRF0457-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | Leptin tA Ovine, PEG |
|---|---|
| Description | |
| Leptin Antagonist Triple Mutant Ovine Recombinant, Pegylated | |
| Synonyms | |
| CDF, HILDA, D-FACTOR, Differentiation- stimulating factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin, Leukemia inhibitory factor, LIF, DIA. | |
| Introduction | |
| Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The LIF protein was lyophilized from 1mg/ml in PBS pH 7.4. | |
| Stability | |
| Lyophilized LIF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution LIF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Biological Activity | |
| The biological activity was determined by its ability to stimulate the proliferation of Human TF-1 cells, the ED 50 is typically less than 0.1ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized LIF in sterile PBS containing 0.1% endotoxin-free recombinant HSA. | |
| Precautions | |
| Leptin tA Ovine, PEG is for research use only and not for use in diagnostic or therapeutic procedures. | |
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ADMEbio Team
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