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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0462-2 | 7 days | 2 µg | $100.00 |
Select product before adding to cart
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| GRF0462-10 | 7 days | 10 µg | $260.00 | |||
| GRF0462-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | OSM Human, HEK |
|---|---|
| Description | |
| Oncostatin-M Human Recombinant, HEK | |
| Accession (Primary) | P13725 |
| Introduction | |
| Ostreolysin is extracted from Pleurotus ostreatus (oyster mushroom). It is a pore forming protein, which contains a lytic part to both cholesterol and sphingomyelin containing membranes. Because of their cholesterol content and the appearance of ostreolysin in the detergent resistant membranes, ostreolysin is cytotoxic towards the ovary cells of Chinese hamster. It seems that Ostreolysin spots a rich lipid cholesterol phase, presumably the liquid ordered phase. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The Ostreolysin protein was lyophilized from a concentrated (1mg/ml) solution with 0.02% NaHCO 3 . | |
| Stability | |
| Lyophilized Pleurotus Ostreatus Ostreolysin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon C between 2-7 days and for future use reconstituted Ostreolysin should be stored at 4°C below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by Gel filtration analysis. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| The N-terminal amino sequence is Ala-Tyr-Ala-Gln-Trp-Val. | |
| Biological Activity | |
| Ostreolysin has potent anti-carcinogenic activity in several colon cancer cell lines. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Ostreolysin in sterile 0.4% NaHCO 3 , not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Protein content | |
| Protein quantitation was carried out by UV spectroscopy at 280 nm using the absorbency value of 2.64 as the extinction coefficient for a 0.1% (1mg/ml) solution at pH 8.0. This value is calculated by the DNA-man computer analysis program. | |
| Precautions | |
| OSM Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P13725 ) | |
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ADMEbio Team
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