| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0473-2 | 7 days | 2 µg | $100.00 |
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| GRF0473-10 | 7 days | 10 µg | $260.00 | |||
| GRF0473-100 | 7 days | 100 µg | $1,600.00 |
Product Overview | |
| Name | TGFB1 Human, GST |
|---|---|
| Description | |
| Transforming Growth Factor-Beta 1 Human Recombinant, GST Tag | |
| Accession (Primary) | P01137 |
| Synonyms | |
| Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1. | |
| Introduction | |
| Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. 3 TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains linked with the latent portion of the molecule. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a sterile filtered solution containing 50mM NaOAc pH-4.5 | |
| Stability | |
| Lyophilized TGFB1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TGFB1 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Biological Activity | |
| The ED 50 as determined by the dose-dependent inhibition of IL-4-induced proliferation of HT-2 cells is 0.15ng/ml, corresponding to a specific activity of 6.6x10 6 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized TGFB1 in sterile 5mM HCL at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| TGFB1 Human, GST is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01137 ) | |
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ADMEbio Team
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ADMEbio Team