| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| GRF0474-2 | 7 days | 2 µg | $100.00 |
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| GRF0474-10 | 7 days | 10 µg | $260.00 | |||
| GRF0474-100 | 7 days | 100 µg | $1,760.00 |
Product Overview | |
| Name | TGFB1 Human, HEK |
|---|---|
| Description | |
| Transforming Growth Factor-Beta 1 Human Recombinant, HEK | |
| Accession (Primary) | P01137 |
| Synonyms | |
| Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3. | |
| Introduction | |
| Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. | |
| Source | |
| Chinese Hamster Ovarian Cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The protein solution contains 20% Ethanol and 0.1% Acetic acid. | |
| Stability | |
| TGF-beta 3 although stable at 4°C. for 3 weeks, should be stored at -20°C to -70°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). | |
| Purity | |
| Greater than 97.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn. | |
| Biological Activity | |
| The biological activity was determined using cell toxicity assay via HT-2 cells. The ED50 was found to be < 0.05ng/ml, corresponding to a specific activity of 20,000,000IU/mg. | |
| Precautions | |
| TGFB1 Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01137 ) | |
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