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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4270-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4270-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | GRP78 BiP (4F11) Mouse mAb |
|---|---|
| Accession (Primary) | P11021 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 72 kDa; Observed MW: 78 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IF-1:50-1:200; IP-1:20 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth. 11587-1-AP antibody recognizes one or two bands with MW 70-78 kDa for the signal peptide of GRP78 protein can be finally cleaved. | |
Target Information: ( P11021 ) | |
| Name | HSPA5 |
| Gene ID | 3309 |
| Other Names | |
| BIP; MIF2; GRP78; FLJ26106; HSPA5; 78 kDa glucose-regulated protein; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein | |
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ADMEbio Team
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ADMEbio Team
