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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| HRM0064-5 | 7 days | 5 mg | $120.00 |
Select product before adding to cart
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| HRM0064-25 | 7 days | 25 mg | $440.00 | |||
| HRM0064-100 | 7 days | 100 mg | $1,040.00 |
Product Overview | |
| Name | Leuprorelin Human |
|---|---|
| Description | |
| Leuprolide Human | |
| Synonyms | |
| Leuprolide, Leuprorelin. | |
| Introduction | |
| Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH). Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The Leuprorelin was lyophilized from a concentrated (1mg/ml) solution with no additives. | |
| Stability | |
| Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by RP-HPLC. | |
| Amino acid sequence | |
| pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Leoprolide in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| Leuprorelin Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
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