Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| HRM0095-100 | 7 days | 100 µg | $440.00 |
Select product before adding to cart
|
||
| HRM0095-500 | 7 days | 500 µg | $1,100.00 | |||
| HRM0095-1 | 7 days | 1 mg | $1,408.00 |
Product Overview | |
| Name | PTH (7-34) Human |
|---|---|
| Description | |
| Parathyroid Hormone (7-34) Human Recombinant | |
| Accession (Primary) | Q03431 |
| Synonyms | |
| PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452. | |
| Introduction | |
| Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. PTH (7-34), which is a PTH/PTHrP receptor antagonist, can stimulate hair growth and epidermal proliferation in mice. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein (1 mg/ml) was lyophilized after extensive dialyses against 20mM PBS pH-7.0 and 150mM NaCl. | |
| Stability | |
| Lyophilized Parathyrin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PTH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| LMHNLGKHLN SMERVEWLRK KLQDVHNF. | |
| Biological Activity | |
| The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 10,000 Units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized PTH in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PTH (7-34) Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q03431 ) | |
Supporting scientific discovery through quality research products.
ADMEbio is committed to supporting scientific research with high-quality research products and laboratory solutions. We welcome publication submissions from researchers who have used our products in their studies. Your work helps advance scientific discovery and enables us to support the research community.
No publications are currently listed for this product.
Have you used this product in your research?
Submit your publication to help share your work with the scientific community.
Share Your Research
Submit your publications and allow other researchers to discover your work.
Advance Scientific Discovery
Help build a growing body of research that supports the scientific community.
Global Research Community
Your publications contribute to real-world research and innovation.
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
