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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| HRM0099-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| HRM0099-50 | 7 days | 50 µg | $290.00 | |||
| HRM0099-1 | 7 days | 1 mg | $2,160.00 |
Product Overview | |
| Name | PTHrP Human |
|---|---|
| Description | |
| Parathyroid Hormone Related Protein Human Recombinant | |
| Accession (Primary) | Q96A98 |
| Synonyms | |
| Parathyroid Hormone 2, PTH2, TIPF39, Tuberoinfundibular 39 Residue Protein. | |
| Introduction | |
| PTHrP is a powerful and discriminating agonist of PTH2R which takes part in adenyl cyclase activation and intracellular calcium levels elevation. PTHrP encourages protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. Additionally, PTHrP inhibits cell proliferation through its contribution to PTH2R activation, activates nociceptors and nociceptive circuits and acts as a neuropeptide in spermatogenesis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| PthRp protein was lyophilized from a 0.2 µm filtered concentrated solution in 1xPBS, pH 7.4. | |
| Stability | |
| Lyophilized PTHrP although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution PTHrP should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized PTHrP in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PTHrP Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96A98 ) | |
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