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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| HRM0100-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| HRM0100-20 | 7 days | 20 µg | $290.00 | |||
| HRM0100-1 | 7 days | 1 mg | $4,800.00 |
Product Overview | |
| Name | PTHrP N15 Human |
|---|---|
| Description | |
| Parathyroid Hormone Related Protein N15 Labeled Human Recombinant | |
| Accession (Primary) | Q96A98 |
| Synonyms | |
| Parathyroid Hormone 2, PTH2, TIPF39, Tuberoinfundibular 39 Residue Protein. | |
| Introduction | |
| PTHrP is a powerful and discriminating agonist of PTH2R which takes part in adenyl cyclase activation and intracellular calcium levels elevation. PTHrP encourages protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. Additionally, PTHrP inhibits cell proliferation through its contribution to PTH2R activation, activates nociceptors and nociceptive circuits and acts as a neuropeptide in spermatogenesis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| PthRp N15 protein was lyophilized from a 0.2 µm filtered concentrated solution in 1xPBS, pH 7.4. | |
| Stability | |
| Lyophilized PTHrP N15 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution PTHrP N15 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP. | |
| Solubility | |
| It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions. | |
| Precautions | |
| PTHrP N15 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96A98 ) | |
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