Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| HRM0111-1 | 7 days | 1 mg | $260.00 |
Select product before adding to cart
|
||
| HRM0111-5 | 7 days | 5 mg | $1,080.00 | |||
| HRM0111-25 | 7 days | 25 mg | $3,040.00 |
Product Overview | |
| Name | Thymosin beta 4 |
|---|---|
| Description | |
| Thymosin β4 | |
| Accession (Primary) | P62328 |
| Synonyms | |
| Thymosin beta-4. TB500, TB-500 | |
| Introduction | |
| Thymosin is a hormone secreted from the thymus. Its primary function is to stimulate the production of T cells, which are an important part of the immune system. Thymosin also assists in the development of B cells to plasma cells to produce antibodies. The predominant form of thymosin, thymosin b4, is a member of a highly conserved family of actin monomer-sequestering proteins. b-thymosins are the primary regulators of unpolymerized actin, and are essential for maintaining the small cytoplasmic pool of free G-actin monomers required for rapid filament elongation and allowing for the flux of monomers between the thymosin-bound pool and F-actin. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein (1mg/ml) was lyophilized with no additives. | |
| Stability | |
| Lyophilized Thymosin b4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution T beta 4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by RP-HPLC. | |
| Amino acid sequence | |
| Thymosin b4 has an a.a. sequence of Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Thymosin beta-4 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| References | |
| Title: Regenerative protein thymosin b -4 is a novel regulator of purinergic signaling. Publication: Published online before printNovember 24, 2010, doi: 10.1096/fj.10-169417 March 2011 The FASEB Journal vol. 25no . 3907-915. Link: Thymosin beta 4 prospec publication | |
| Precautions | |
| Thymosin beta 4 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P62328 ) | |
References |
Title: Regenerative protein thymosin b -4 is a novel regulator of purinergic signaling. Publication: Published online before printNovember 24, 2010, doi: 10.1096/fj.10-169417 March 2011 The FASEB Journal vol. 25no . 3907-915. Link: Thymosin beta 4 prospec publication |
Supporting scientific discovery through quality research products.
ADMEbio is committed to supporting scientific research with high-quality research products and laboratory solutions. We welcome publication submissions from researchers who have used our products in their studies. Your work helps advance scientific discovery and enables us to support the research community.
No publications are currently listed for this product.
Have you used this product in your research?
Submit your publication to help share your work with the scientific community.
Share Your Research
Submit your publications and allow other researchers to discover your work.
Advance Scientific Discovery
Help build a growing body of research that supports the scientific community.
Global Research Community
Your publications contribute to real-world research and innovation.
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
