| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1070-5 | 7 days | 5 µg | $120.00 |
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| RCP1070-25 | 7 days | 25 µg | $290.00 | |||
| RCP1070-1 | 7 days | 1 mg | $3,600.00 |
Product Overview | |
| Name | HSP27 Human, His |
|---|---|
| Description | |
| Heat Shock Protein 27 Human Recombinant, His Tag | |
| Accession (Primary) | P04792 |
| Synonyms | |
| HSPB1, CMT2F, HMN2B, HSP27, HSP28, HSP25, Heat shock protein beta-1, Heat shock 27 kDa protein, Stress-responsive protein 27, SRP27, HS.76067, DKFZp586P1322. | |
| Introduction | |
| HSP27 or Estrogen-Regulated 24K proteinis a part of the mammalian small heat shock protein family. The protein is expressed constitutively in many tissues and its expression is increased to high levels after different types of stress including high temperatures, toxic metals, drugs and oxidants. Furthermore, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The HSP27 protein solution (1mg/ml) contains 20mM Tris-HCl (pH8.0), 10% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MTERRVP FSLLRSPSWE PFRDWYPAHS RLFDQAFGVP RLPDEWSQWF SAAGWPGYVR PLPAATAEGP AAVTLAAPAF SRALNRQLSS GVSEIRQTAD RWRVSLDVNH FAPEELTVKT KEGVVEITGK HEERQDEHGY ISRCFTRKYT LPPGVDPTLV SSSLSPEGTL TVEAPLPKAV TQSAEITIPV TFEARAQIGG PEAGKSEQSG AK. | |
| Precautions | |
| HSP27 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P04792 ) | |
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