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IGF2 Human

IGF-2 Human Recombinant

 
Catalog #
GRF0173
Uniprot Id
P01344
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
GRF0173-10 7 days 10 µg $120.00
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GRF0173-50 7 days 50 µg $290.00
GRF0173-1 7 days 1 mg $2,016.00
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Product Overview

NameIGF2 Human
Description
IGF-2 Human Recombinant
Accession (Primary)P01344
Synonyms
Somatomedin-A, IGF2, INSIGF, pp9974, C11orf43, FLJ22066, FLJ44734
Introduction
Insulin-like growth factor II (IGF-II) is an important foetal growth hormone.IGF-II is made by theca cells during gestation. IGF-II binds the sink IGF-II receptor (IGF2R) which results in IGF-II degradation.IGF-II also engages the IGF-I receptor (IGF1R) to arbitrate embryonic growth.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a sterile (0.2 µ) filtered solution containing 0.1 % trifluoroacetic acid (TFA).
Stability
Lyophilized IGF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGF2 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
AYGPGETLCG GELVDTLQFV CSDRGFYFSR PSSRANRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Biological Activity
The ED 50 as determined by FDC-P1 cell proliferation is ≤ 50 ng/mL, corresponding to a specific activity of ≥ 2.0 x 10^4 units/mg.
Solubility
It is recommended to reconstitute the lyophilized IGF2 in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions.
Precautions
IGF2 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P01344 )

References

Title: Sub-Cellular Localisation Studies May Spuriously Detect the Yes-Associated Protein, YAP Publications: Nucleoli Leading to Potentially Invalid Conclusions of Its Function. PLoS ONE 10.2 (2015): e0114813. Link: IGF2 prospec publication

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