| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1130-10 | 7 days | 10 µg | $120.00 |
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| RCP1130-50 | 7 days | 50 µg | $290.00 | |||
| RCP1130-1 | 7 days | 1 mg | $2,880.00 |
Product Overview | |
| Name | IPP-POZ Human |
|---|---|
| Description | |
| IPP-POZ Human Recombinant | |
| Accession (Primary) | Q9Y573 |
| Synonyms | |
| IRF-2, IRF2, MAR, DKFZp686F0244, IFN regulatory factor 2. | |
| Introduction | |
| IFN regulatory factor 2 is a member of the IFN regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of IFNs alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. IRF2 binds to the upstream regulatory region of type-1 IFN and IFN-inducible MHC class-1 genes (the IFN consensus sequence (ics) and represses those genes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| 1 mg/ml in 20mM Tris pH-8, 1mM DTT and 10% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMHAARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIKKGNNAFRVYR MLP. | |
| Precautions | |
| IPP-POZ Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9Y573 ) | |
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