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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3321-100 | 2 weeks | 100 µL | $499.00 |
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|
||
| ABZ3321-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Insulin degrading enzyme Rabbit mAb |
|---|---|
| Accession (Primary) | P14735 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 118 kDa; Observed MW: 118 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; ICC/IF-1:20; FC-1:20 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. | |
Target Information: ( P14735 ) | |
| Name | IDE |
| Gene ID | 3416 |
| Other Names | |
| INSULYSIN; Insulin degrading enzyme; IDE; Abeta-degrading protease; FLJ35968; Ide; | |
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ADMEbio Team
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ADMEbio Team
