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[KD]TCTEX-1 Rabbit mAb

Catalog #: ABZ4767
Application: WB, IF, FC, IP, ICC, IHC-F, IHC-P
Uniprot Id: P63172
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Immunocytochemistry analysis of Dynein Light Chain Tctex Type 1 (green) in Hela using Dynein Light Chain Tctex Type 1 antibody,and DAPI(blue).
Western blot analysis of TCTEX1 in 3T3, C6 lysates using TCTEX1 antibody.
Western blot analysis of TCTEX1 in Hela, A549, HL-60 lysates using TCTEX1 antibody
Immunohistochemistry analysis of paraffin-embedded Human tonsil using TCTEX1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KD]TCTEX-1 Rabbit mAb
Accession (Primary)	P63172
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 12 kDa; Observed MW: 12 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:20-1:50; ICC/IF-1:200-1:500; FC-1:50-1:100; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Target Information: ( P63172 )
Name	DYNLT1
Gene ID	6993
Other Names
TCTEL1; TCTEX-1; TCTEX1,DYNLT1,Protein CW-1,T-complex testis-specific protein 1 homolog

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